Overview

Inflammation is part of healing — but when it drags on, it causes pain and slows repair. HBOT delivers concentrated oxygen that helps your body settle inflammation naturally. It reduces the chemicals that drive swelling while improving blood flow and tissue repair.

How this might help

More oxygen allows your body to clear waste and calm irritation faster. HBOT has been shown to lower inflammation markers and promote faster recovery from surgery, injury, and strenuous training. It’s a simple way to support comfort and recovery without relying on medication.

Selected Research Studies

(For clinicians and advanced readers)

Meng XE, Zhang Y, Li N, et al. Hyperbaric oxygen alleviates secondary brain injury after trauma through inhibition of TLR4/NF-κB signaling pathway. Med Sci Monit. 2016;22:284–288. Published 2016 Jan 26. doi:10.12659/msm.894148

Dulai PS, Gleeson MW, Taylor D, et al. (2014), Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease. Aliment Pharmacol Ther, 39: 1266-1275. doi:10.1111/apt.12753

Hui J, Zhang ZJ, Zhang X, et al. Repetitive hyperbaric oxygen manage attenuates complete Freund’s adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord, J. Pain, 14 (7) (2013), pp. 747-758

Li F, Fang L, Huang S, et al. Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and reduces tumor necrosis factor-alpha production. Anesth. Analg., 113 (3) (2011), pp. 626-633

Choudhury R. Hypoxia and hyperbaric oxygen therapy: a review. Int J Gen Med. 2018;11:431–442. Published 2018 Nov 20. doi:10.2147/IJGM.S172460

He H, Li X, He Y. Hyperbaric oxygen therapy attenuates neuronal apoptosis induced by traumatic brain injury via Akt/GSK3β/β-catenin pathway. Neuropsychiatr Dis Manage. 2019;15:369–374. Published 2019 Jan 25. doi:10.2147/NDT.S183632

Wu HH, Huang CC, Chang CP, et al. Heat shock protein 70 (HSP70) reduces hepatic inflammatory and oxidative damage in a rat model of liver ischemia/reperfusion injury with hyperbaric oxygen preconditioning. Med Sci Monit. 2018;24:8096–8104. Published 2018 Nov 12. doi:10.12659/MSM.911641

Thompson CD, Uhelski ML, Wilson JR, et al. Hyperbaric oxygen manage decreases pain in two nerve injury models. Neurosci. Res., 66 (3) (2010), pp. 279-283

Oyaizu T, Enomoto M, Yamamoto N, et al. Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation. Sci Rep. 2018;8(1):1288. Published 2018 Jan 22. doi:10.1038/s41598-018-19670-x

Zhao BS, Meng LX, Ding YY, et al. Hyperbaric oxygen manage produces an antinociceptive response phase and inhibits astrocyte activation and inflammatory response in a rat model of neuropathic pain. J. Mol. Neurosci., 53 (2) (2014), pp. 251-261

Novak S, Drenjancevic I, Vukovic R, et al. Anti-inflammatory effects of hyperbaric oxygenation during DSS-induced colitis in BALB/c mice include changes in gene expression of HIF-1α, proinflammatory cytokines, and antioxidative enzymes. Mediators Inflamm. 2016;2016:7141430. doi:10.1155/2016/7141430

Hou S, Wu G, Liang J, et al. Hyperbaric oxygen on rehabilitation of brain tumors after surgery and effects on TNF-α and IL-6 levels. Oncol Lett. 2019;17(3):3277–3282. doi:10.3892/ol.2019.10000

Di Sabato F, Rocco M, Martelletti P, et al. Hyperbaric oxygen in chronic cluster headaches: influence on serotonergic pathways. Undersea Hyperb. Med., 24 (2) (1997), pp. 117-122

Bennett MH, French C, Schnabel A, et al. Normobaric and hyperbaric oxygen therapy for migraine and cluster headache. Cochrane Database Syst. Rev. (3)(2008). 

Fosen KM, Thom SR. Hyperbaric oxygen, vasculogenic stem cells, and wound healing. Antioxid Redox Signal. 2014;21(11):1634–1647. doi:10.1089/ars.2014.5940

Overview

Every cell in your body runs on energy made from oxygen. When you’re stressed, injured, or tired, those energy systems slow down. HBOT increases oxygen in the bloodstream, helping your cells produce more of the energy they need to heal, think, and move.

How this might help

With more oxygen to work with, cells can recover faster and perform better. Studies show HBOT boosts energy production, supports stem-cell activity, and reduces oxidative stress. Over time, that can mean better focus, quicker recovery, and more sustained physical and mental energy.

Selected Research Studies

(For clinicians and advanced readers)
Palzur E, Zaaroor M, Vlodavsky E, et al. Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties. Brain Res., 1221 (2008), pp. 126-133

K.R. Dave, R. Prado, R. Busto, A.P. Raval, W.G. Bradley, D. Torbati, M.A. Pérez-pinzón,

Hyperbaric oxygen therapy protects against mitochondrial dysfunction and delays onset of motor neuron disease in wobbler mice, Neuroscience, Volume 120, Issue 1, 2003, Pages 113-120,

ISSN 0306-4522, https://doi.org/10.1016/S0306-4522(03)00244-6.

Meyer JN, Hartman JH, Mello DF. Mitochondrial toxicity. Toxicological Sciences, Volume 162, Issue 1, March 2018, Pages 15–23.

Meyer JN, Leung MC, Rooney JP, et al. Mitochondria as a target of environmental toxicants. Toxicol Sci. 2013;134(1):1–17. doi:10.1093/toxsci/kft102

Overview

Your immune system needs oxygen to fight infection and repair damage efficiently. HBOT increases oxygen in the blood, giving white blood cells the power to kill bacteria and remove waste while reducing excess inflammation. It also activates stem cells and growth factors that rebuild damaged tissue.

How this might help

HBOT strengthens your natural defence and repair systems. Clinical research shows it improves wound closure, helps fight infection, and supports new blood-vessel growth in oxygen-starved tissues. It’s a proven hospital therapy for stubborn wounds and a powerful recovery aid in wellness settings.

Selected Research Studies

(For clinicians and advanced readers)

Çimşit M, Uzun G, Yıldız S. Hyperbaric oxygen therapy as an anti-infective agent. Expert Rev Anti Infect Ther. 2009;7(8):1015–1026.

Memar MY, Yekani M, Alizadeh N, et al. Hyperbaric oxygen therapy: antimicrobial mechanisms and clinical application for infections. Biomed Pharmacother. 2019;109:440–447.

Mader JT, Brown GL, Guckian JC, et al. A mechanism for the amelioration by hyperbaric oxygen of experimental staphylococcal osteomyelitis in rabbits. J Infect Dis. 1980;142(6):915–922.

Fosen KM, Thom SR. Hyperbaric oxygen, vasculogenic stem cells, and wound healing. Antioxid Redox Signal. 2014;21(11):1634–1647.

Health Quality Ontario. Hyperbaric oxygen therapy for the management of diabetic foot ulcers: a health technology assessment. Ont Health Technol Assess Ser. 2017;17(5):1–142.

Oyaizu T, Enomoto M, Yamamoto N, et al. Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation. Sci Rep. 2018;8(1):1288.

Overview

Your brain never stops adapting — it constantly builds new connections to learn, think, and remember. Hyperbaric oxygen therapy (HBOT) gives your brain extra oxygen, helping nerve cells get the fuel they need to repair and grow. This can support clearer thinking, better focus, and faster recovery after injury or illness.

How this might help

By improving blood flow and giving neurons more oxygen, HBOT helps the brain “wake up” sluggish areas and strengthen communication between cells. Studies show improvements in memory, attention, and reaction time in older adults and people recovering from brain injuries. It’s a natural way to help the brain restore balance and function at its best.

Selected Research Studies

(For clinicians and advanced readers)

Efrati S, Fishlev G, Bechor Y, et al. Hyperbaric oxygen induces late neuroplasticity in post stroke patients–randomized, prospective trial. PLoS One. 2013;8(1):e53716.

Boussi-Gross R, Golan H, Fishlev G, et al. Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury – randomized prospective trial. PLoS One. 2013;8(11):e79995.

Vadas D, Kalichman L, Hadanny A, et al. Hyperbaric oxygen environment can enhance brain activity and multitasking performance. Front Integr Neurosci. 2017;11:25.

Thom SR. Hyperbaric oxygen: its mechanisms and efficacy. Plast Reconstr Surg. 2011;127(Suppl 1):131S–141S.

Tal S, Hadanny A, Sasson E, et al. Hyperbaric oxygen therapy can induce angiogenesis and regeneration of nerve fibers in traumatic brain injury patients. Front Hum Neurosci. 2017;11:508.

Overview

Collagen is what keeps your skin, muscles, and joints strong — it’s the body’s built-in scaffolding. HBOT supports collagen production by flooding tissues with oxygen and activating the cells that rebuild connective tissue. It also helps tiny new blood vessels form, bringing more nutrients to healing areas.

How this might help

More oxygen means faster, stronger repair. HBOT speeds up wound healing, helps grafts and skin repairs take hold, and supports post-surgery recovery by improving collagen quality and strength. It’s widely used in hospitals for slow-healing wounds and increasingly explored in recovery and cosmetic settings.

Selected Research Studies

(for clinicians and advanced readers)

Bhutani S, Vishwanath G. Hyperbaric oxygen and wound healing. Indian J Plast Surg. 2012;45(2):316–324.

Fosen KM, Thom SR. Hyperbaric oxygen, vasculogenic stem cells, and wound healing. Antioxid Redox Signal. 2014;21(11):1634–1647.

Oyaizu T, Enomoto M, Yamamoto N, et al. Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation. Sci Rep. 2018;8(1):1288.

Perren S, Gatt A, Papanas N, et al. Hyperbaric oxygen therapy in ischaemic foot ulcers in type 2 diabetes: a clinical trial. 

Health Quality Ontario. Hyperbaric oxygen therapy for the management of diabetic foot ulcers: a health technology assessment. Ont Health Technol Assess Ser. 2017;17(5):1–142.

Eskes AM, Ubbink DT, Lubbers MJ, et al. Hyperbaric oxygen therapy: solution for difficult to heal acute wounds? Systematic review. World J Surg. 2011;35(3):535–542.

Fujita N, Ono M, Tomioka T, et al. Effects of hyperbaric oxygen at 1.25 atmospheres absolute with normal air on macrophage number and infiltration during rat skeletal muscle regeneration. PLoS One. 2014;9(12):e115685.

Overview

Lingering inflammation can make you sore and slow down healing. Red light therapy helps calm that response by improving circulation and supporting your body’s natural antioxidant defences.

How this might help

With better blood flow and less cellular stress, pain and swelling ease more quickly. Studies show red light therapy reduces soreness after exercise, speeds tissue recovery, and helps your body return to balance — naturally, without medication.

Selected Research Studies

(for clinicians and advanced readers)

Marashian SM, Hashemian MR, Pourabdollah M, et al. Photobiomodulation improves serum cytokine response in mild to moderate COVID-19: The first randomized, double-blind, placebo-controlled, pilot study. Frontiers in Immunology. 2022;13:929837. Published July 8, 2022.

Zwiri AMA, Ahmad WMAW, Asif JA, et al. A randomized controlled trial evaluating the biomarkers hs‑CRP, IL‑6, and IL‑8 in patients with temporomandibular disorder treated with LLLT, conservative therapy, and combination therapy. International Journal of Environmental Research and Public Health. 2022;19(15):8987. Published July 23, 2022.

Lim W, Lee S, Kim I, et al. Photobiomodulation suppresses neuroinflammation and attenuates symptoms in chronic neuropathic pain: A randomized, placebo-controlled trial. Pain Medicine. 2023;24(5):979–988. Published May 2023

Nunes EC, Nascimento DP, Silva Júnior HD, et al. Effectiveness of photobiomodulation therapy in the management of pain and inflammation after dental implant surgery: a randomized single-blind clinical trial. J Clin Med. 2022;13(19):5709. Published October 1 2022.

de Oliveira BP, de Almeida LM, Leal-Junior ECP, et al. Effects of infrared low-level laser therapy applied prior to an intense progressive running test on inflammatory and oxidative stress markers in high-level soccer players: a randomized, triple-blind, crossover trial. Oxid Med Cell Longev. 2019;2019:6239058. Published December 5 2019.

Overview

Every cell in your body needs energy to function. Red and near-infrared light act like a natural spark, helping your cells make more of it. When light reaches your tissues, it supports the tiny “power centres” inside each cell, improving how efficiently your body produces and uses energy.

How this might help

More cell energy means more vitality. Red light therapy can improve endurance, speed recovery, and enhance focus — all by helping your body’s energy systems run more smoothly. It’s a safe, non-invasive way to boost performance and resilience.

Selected Research Studies

(for clinicians and advanced readers)

Fritsch CG, Dornelles MP, Teodoro JL, et al. Effects of photobiomodulation therapy associated with resistance training in elderly men: a randomized double-blinded placebo-controlled trial. Eur J Appl Physiol. 2019;119(1):279–289. Published 2018 Oct 26.

Tomazoni SS, Monteiro Machado CS, De Marchi T, et al. Infrared low-level laser therapy (photobiomodulation) before an intense progressive running test in high-level soccer players: randomized, triple-blind, crossover trial. Oxid Med Cell Longev. 2019;2019:6239058. Published 2019 Dec 5.

Lanferdini FJ, Krüger RL, Baroni BM, et al. Pre-exercise photobiomodulation accelerates pulmonary oxygen uptake kinetics and increases tolerance to high-intensity exercise. Eur J Appl Physiol. 2023;123(3):701–713. Published 2023 Jan 5.

Giménez MC, Lindhouse OAM, Nuijten MAH, et al. Effects of near-infrared light on well-being and health in human subjects with mild sleep-related complaints: a double-blind, randomized, placebo-controlled study. Int J Environ Res Public Health. 2023;20(1):878. Published 2023 Jan 4.

Nakhostin-Roohi B, Delpasand A, Candow DG, et al. Photobiomodulation therapy and exercise performance: a systematic review and meta-analysis of randomized controlled trials. Sports Med. 2025;55(6):497–520. Published 2025 Apr 10.

Overview

Your immune system works best when it’s balanced — strong enough to protect you, but not overactive. Red light therapy helps achieve that balance by calming unnecessary inflammation and supporting your cells’ ability to repair themselves.

How this might help

More efficient cell energy and smoother immune signalling mean quicker recovery from stress, training, or illness. Research shows red light therapy can reduce swelling, improve wound healing, and help your body stay in a balanced, healthy repair state.

Selected research studies

(for clinicians and advanced readers)

Özberk SS, Yıldırım A, Tonguç E, et al. Effect of adjunctive photobiomodulation therapy on nonsurgical periodontal treatment in patients with type 2 diabetes mellitus: a randomized controlled, single-blind, split-mouth clinical trial. Photodiagnosis Photodyn Ther. 2020;32:101962. Published 2020 Oct 23.

Al Balah OF, Rafie M, Osama A-R. Immunomodulatory effects of photobiomodulation: A comprehensive review. Lasers in Medical Science. 2025;40(1):187. Published April 11, 2025.

Camolesi B, Fragni M, Ferrando S, et al. Photobiomodulation therapy after dental implant placement reduces postoperative inflammation and pain: a randomized controlled split-mouth study. Lasers Med Sci. 2022;37(6):2547–2556. Published 2022 Mar 29.

Chia WT, Wong TH, Jaw FS, Hsieh HC. The impact of photobiomodulation therapy on swelling reduction and recovery enhancement in total knee arthroplasty: a randomized clinical trial. Photobiomodul Photomed Laser Surg. 2025;43(2):65–72. Published 2025 Jan 9.   

Photobiomodulation Improves Serum Cytokine Response in Mild to Moderate COVID-19: The First Randomized, Double-Blind, Placebo Controlled, Pilot Study – Seyed Mehran Marashian et al., 2022, Frontiers in Immunology. DOI: 10.3389/fimmu.2022.929837 

Efficacy of Using Photobiomodulation Therapy in Allergic Rhinitis: A Placebo-Controlled Randomized Clinical Trial – Patrícia C. Oliveira et al., 2025, International Forum of Allergy & Rhinology. DOI: 10.1002/alr.23532 

Overview

Your brain depends on steady energy to stay focused and alert. Red light therapy, especially when applied to the head, helps brain cells use oxygen more efficiently and encourages better blood flow. This can support sharper thinking, improved mood, and mental clarity.

How this might help

Red light therapy “recharges” your brain’s energy systems, helping neurons communicate more effectively. Early studies show improvements in focus, reaction time, and mood, making it a gentle, non-invasive way to support cognitive performance.

Selected Research Studies

(for clinicians and advanced readers)

Zhao C, Li D, Kong Y, et al. Transcranial photobiomodulation enhances visual working memory capacity in humans. Science Advances. 2022;8(48):eabq3211. Published December 2, 2022 .

Lee TL, Ding Z, Chan AS. Can transcranial photobiomodulation improve cognitive function? A systematic review of human studies. Ageing Research Reviews. 2023;83:101786. Published online November 9, 2022 .

Ji Q, Yan S, Ding J, et al. Photobiomodulation improves depression symptoms: A systematic review and meta-analysis of randomized controlled trials. Frontiers in Psychiatry. 2024;14:1267415. Published January 31, 2024 .

Longo MGF, Tan CO, Chan ST, et al. Effect of transcranial low-level light therapy vs sham therapy among patients with moderate traumatic brain injury: A randomized clinical trial. JAMA Network Open. 2020;3(9):e2017337. Published September 1, 2020 .

Overview

Red and near-infrared light gently energise the cells that build and repair your body’s tissues. When these wavelengths reach the skin and muscles, they help fibroblasts — the cells that make collagen — work faster and more efficiently. The result is improved healing, better skin tone, and stronger connective tissue.

How this might help

By giving your cells more usable energy, red light therapy helps wounds close quicker and supports recovery after training or surgery. It’s widely used to speed tissue repair, reduce scarring, and rejuvenate skin by encouraging healthy collagen formation.

Selected Research Studies

(for clinicians and advanced readers)

Mota LR, Duarte IS, Galache TR, et al. Photobiomodulation reduces periocular wrinkle volume by 30%: a randomized controlled trial. Photobiomodul Photomed Laser Surg. 2023;41(2):48–56. Published 2023 Feb. doi:10.1089/photob.2022.0114.

Torkaman AY, Amiri R, Ilbeigi P, et al. The effects of photobiomodulation therapy on clinical healing of diabetic foot ulcers: a randomized, double-blind, controlled clinical trial. J Wound Care. 2024;33(4):258–267. Published 2024 Mar 27. doi:10.12968/jowc.2024.33.4.258.

Yadav D, Sharma AK, Tripathi K, et al. Effects of photobiomodulation adjunct therapy via superpulsed 904 nm laser in patients with second-degree burns: randomized controlled clinical trial. Journal of Biophotonics. 2025;e202500386. Published online September 24, 2025 .

Taha N, Daoud H, Malik T, Shettysowkoor J, Rahman S. The effects of low-level laser therapy on wound healing and pain management in skin wounds: A systematic review and meta-analysis. Cureus. 2024;16(10):e72542. Published October 28, 2024 .

Kurtti A, Laskin J, Jagdeo J, et al. Dose-ranging study of red light-emitting diode phototherapy for reduction of post-surgical scarring. J Biophotonics. 2021;14(7):e202100073.

Wunsch A, Matuschka K. A controlled trial to determine the efficacy of red and near-infrared light treatment for skin rejuvenation. Photomed Laser Surg. 2014;32(2):93–100.