Hyperbaric oxygen therapy has shown promising benefits for treating hard-to-heal wounds, particularly those that persist due to chronic inflammation. By increasing the amount of oxygen in the blood, HBOT helps boost the body's natural healing processes. It has been found to reduce harmful inflammation by lowering the levels of certain chemicals in the body that promote inflammation, while simultaneously increasing the production of growth factors that aid in tissue repair. This dual action can accelerate wound healing and potentially lead to better outcomes for patients with stubborn wounds that haven't responded to other treatments.

• Hyperbaric Oxygen Therapy (HBOT)
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• Increased Oxygen Levels in Blood
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• Effects on Chemical Mediators:

• Reduces Proinflammatory Cytokines (e.g., TNF-α)
• Increases Growth Factors (e.g., VEGF)
• Reduces Prostaglandins (e.g., PGE2, COX-2 mRNA) ↓

• Reduced Inflammation
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• Enhanced Wound Healing
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• Improved Healing of Hard-to-Heal Wounds

To gain a deeper understanding of the process visit the article at https://pubmed.ncbi.nlm.nih.gov/16604253/.